TECHNOLOGICAL AND BIOPHARMACEUTICAL ADVANTAGES OF SUPPOSITORIES PRODUCED IN UZBEKISTAN AND EUROPE: A COMPARATIVE STATISTICAL ANALYSIS.

Abstract

Suppositories represent one of the widely used dosage forms in modern pharmaceutical practice, particularly in pediatrics, gynecology, and proctology. This study presents a comparative statistical analysis of the technological, biopharmaceutical, and economic characteristics of suppositories manufactured in Uzbekistan and European countries. The results demonstrated that the average bioavailability of European-manufactured suppositories reached 96%, whereas in Uzbekistan this indicator ranged from 88% to 90%. The stability of suppositories was 97% in Europe and 88% in Uzbekistan, respectively [1,2]. These findings indicate significant technological differences between the regions and highlight the importance of implementing advanced pharmaceutical manufacturing standards.