FUNCTIONAL DISORDERS OF THE BILIARY TRACT IN CHILDREN: CLINICO-PATHOGENETIC CORRELATIONS, DIAGNOSTIC INFORMATIVENESS, AND EFFECTIVENESS OF COMPLEX THERAPY

Abstract

The aim of the study was to investigate the clinical manifestations, diagnostic value of various methods, and the effectiveness of complex therapy in children with functional disorders of the biliary tract (FDBT). The study included 68 patients aged 6–15 years diagnosed with gallbladder dysfunction or sphincter of Oddi dysfunction. The main clinical manifestations were abdominal pain syndrome (61%), dyspeptic disorders (47%), astheno-neurotic symptoms (32%), and autonomic dysfunction (18%). The most informative diagnostic method was the ultrasound cholecystokinetic test, with a sensitivity of 72%, which exceeded that of standard ultrasonography (38%). Treatment included dietary therapy, pharmacological agents (antispasmodics, cholekinetics, ursodeoxycholic acid), and physiotherapeutic methods. After 3 months, stable clinical improvement was observed in 79% of patients, with the highest effectiveness achieved through complex therapy (86%). The results emphasize the importance of early diagnosis and a comprehensive therapeutic approach in children with FDBT.