CLINICAL PHARMACOLOGY OF ANTI-INFLAMMATORY DRUGS

Abstract

Anti-inflammatory drugs are among the most commonly used medications worldwide, but their use remains complex due to their diverse mechanisms, therapeutic effects, and side effects. This article aims to examine the clinical pharmacology of anti-inflammatory drugs with a focus on current findings and practical implications. It explores the mechanisms of action, clinical uses, pharmacokinetics, and risks associated with non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. A special attention is given to the development of selective COX-2 inhibitors and emerging therapies. The findings suggest that despite progress in safer drug development, responsible and individualized use remains critical to reduce adverse events.