JASET

THE IMPACT OF OBESITY ON HORMONAL IMBALANCE AND METABOLIC HEALTH IN ADULTS

Authors

  • Ulugbek Qobilov

    Chirchiq Branch, Tashkent State Medical University, Tashkent Uzbekistan
    Author

Keywords:

Obesity, hormonal imbalance, insulin resistance, metabolic syndrome, endocrine health, lifestyle factors, adult population.

Abstract

Obesity is a global public health concern that significantly affects endocrine and metabolic health. Excess adiposity disrupts hormonal balance, leading to insulin resistance, altered sex hormone levels, thyroid dysfunction, and increased risk of metabolic syndrome. This review article systematically examines the mechanisms through which obesity contributes to hormonal imbalances and their clinical consequences.

The interaction between adipose tissue, inflammatory cytokines, and endocrine organs is highlighted, demonstrating how chronic low-grade inflammation exacerbates metabolic disturbances. Additionally, lifestyle factors, including diet, physical inactivity, and sedentary behavior, are analyzed for their role in obesity-induced endocrine dysfunction. The article emphasizes the importance of early detection, weight management, and lifestyle modification in preventing long-term metabolic complications and promoting

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Published

2025-10-27